This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3tt7

From Proteopedia

Revision as of 07:33, 30 June 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 3tt7

Contents

Structure of ClpP from Bacillus subtilis in complex with DFP

Template:ABSTRACT PUBMED 22080375

Function

[CLPP_BACSU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.[1]

About this Structure

3tt7 is a 7 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

  • Lee BG, Kim MK, Song HK. Structural insights into the conformational diversity of ClpP from Bacillus subtilis. Mol Cells. 2011 Nov 9. PMID:22080375 doi:10.1007/s10059-011-0197-1
  1. ↑ Zellmeier S, Schumann W, Wiegert T. Involvement of Clp protease activity in modulating the Bacillus subtilissigmaw stress response. Mol Microbiol. 2006 Sep;61(6):1569-82. Epub 2006 Aug 8. PMID:16899079 doi:MMI5323

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3tt7"
Personal tools