3v00

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Template:STRUCTURE 3v00

Contents

Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.

Template:ABSTRACT PUBMED 22448927

Function

[GNAT1_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

About this Structure

3v00 is a 3 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Singh G, Ramachandran S, Cerione RA. A constitutively active galpha subunit provides insights into the mechanism of g protein activation. Biochemistry. 2012 Apr 17;51(15):3232-40. Epub 2012 Apr 5. PMID:22448927 doi:10.1021/bi3001984

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OCA

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