4b53

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Template:STRUCTURE 4b53

Crystal structure of the isolated IgG4 CH3 domain

Template:ABSTRACT PUBMED 23164605

About this Structure

4b53 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Davies AM, Rispens T, den Bleker TH, McDonnell JM, Gould HJ, Aalberse RC, Sutton BJ. Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange. Mol Immunol. 2012 Nov 16;54(1):1-7. doi: 10.1016/j.molimm.2012.10.029. PMID:23164605 doi:10.1016/j.molimm.2012.10.029

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