4bin

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Template:STRUCTURE 4bin

Contents 1 Crystal structure of the E. coli N-acetylmuramoyl-L-alanine amidase AmiC 2 Function 3 About this Structure 4 Reference

Crystal structure of the E. coli N-acetylmuramoyl-L-alanine amidase AmiC

Template:ABSTRACT PUBMED 23927005

Function

[AMIC_ECOLI] Cell-wall hydrolase involved in septum cleavage during cell division. Can also act as powerful autolysin in the presence of murein synthesis inhibitors.^{[1] [2]}

About this Structure

4bin is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

• Rocaboy M, Herman R, Sauvage E, Remaut H, Moonens K, Terrak M, Charlier P, Kerff F. The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain. Mol Microbiol. 2013 Aug 8. doi: 10.1111/mmi.12361. PMID:23927005 doi:10.1111/mmi.12361

1. ↑ Heidrich C, Templin MF, Ursinus A, Merdanovic M, Berger J, Schwarz H, de Pedro MA, Holtje JV. Involvement of N-acetylmuramyl-L-alanine amidases in cell separation and antibiotic-induced autolysis of Escherichia coli. Mol Microbiol. 2001 Jul;41(1):167-78. PMID:11454209
2. ↑ Uehara T, Park JT. Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J Bacteriol. 2008 Jun;190(11):3914-22. doi: 10.1128/JB.00207-08. Epub 2008 Apr 4. PMID:18390656 doi:10.1128/JB.00207-08