4bx9

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Template:STRUCTURE 4bx9

Contents

Human Vps33A in complex with a fragment of human Vps16

Template:ABSTRACT PUBMED 23901104

Function

[VP33A_HUMAN] May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes (By similarity). [VPS16_HUMAN] May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.

About this Structure

4bx9 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Graham SC, Wartosch L, Gray SR, Scourfield EJ, Deane JE, Luzio JP, Owen DJ. Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. Proc Natl Acad Sci U S A. 2013 Jul 30. PMID:23901104 doi:10.1073/pnas.1307074110

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