4bht

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Template:STRUCTURE 4bht

Contents 1 Structural Determinants of Cofactor Specificity and Domain Flexibility in Bacterial Glutamate Dehydrogenases 2 Function 3 About this Structure 4 Reference

Structural Determinants of Cofactor Specificity and Domain Flexibility in Bacterial Glutamate Dehydrogenases

Template:ABSTRACT PUBMED 23879525

Function

[DHE4_ECOLI] Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.^{[1] [2]}

About this Structure

4bht is a 6 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2yfg. Full crystallographic information is available from OCA.

Reference

• Sharkey MA, Oliveira TF, Engel PC, Khan AR. Structure of NADP -dependent glutamate dehydrogenase from Escherichia coli: Reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases. FEBS J. 2013 Jul 23. doi: 10.1111/febs.12439. PMID:23879525 doi:10.1111/febs.12439

1. ↑ Veronese FM, Boccu E, Conventi L. Glutamate dehydrogenase from Escherichia coli: induction, purification and properties of the enzyme. Biochim Biophys Acta. 1975 Feb 19;377(2):217-28. PMID:235298
2. ↑ Sakamoto N, Kotre AM, Savageau MA. Glutamate dehydrogenase from Escherichia coli: purification and properties. J Bacteriol. 1975 Nov;124(2):775-83. PMID:241744