3zk1
From Proteopedia
Contents |
Crystal structure of the sodium binding rotor ring at pH 5.3.
Template:ABSTRACT PUBMED 23824040
Function
[ATPL_FUSNN] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits (By similarity).
About this Structure
3zk1 is a 22 chain structure with sequence from Fusobacterium nucleatum. Full crystallographic information is available from OCA.
Reference
- Schulz S, Iglesias-Cans M, Krah A, Yildiz O, Leone V, Matthies D, Cook GM, Faraldo-Gomez JD, Meier T. A new type of na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif. PLoS Biol. 2013 Jun;11(6):e1001596. doi: 10.1371/journal.pbio.1001596. Epub 2013 , Jun 25. PMID:23824040 doi:10.1371/journal.pbio.1001596
