4bil

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Template:STRUCTURE 4bil

Contents

Threading model of the T7 large terminase within the gp8gp19 complex

Template:ABSTRACT PUBMED 23632014

Function

[VDMB_BPT7] During the growth of this phage, DNA is synthesized as concatemers. During DNA packaging mature monomers are cut from the concatemers. Gp19 is a nonspecific endonuclease that cause double stranded breaks. Its activity is suppressible by either ATP or gp18.

About this Structure

4bil is a 5 chain structure with sequence from Enterobacteria phage t7. Full crystallographic information is available from OCA.

Reference

  • Dauden MI, Martin-Benito J, Sanchez-Ferrero JC, Pulido-Cid M, Valpuesta JM, Carrascosa JL. Large terminase conformational change induced by connector binding in bacteriophage T7. J Biol Chem. 2013 Apr 30. PMID:23632014 doi:10.1074/jbc.M112.448951

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OCA

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