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4bwf

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Revision as of 18:56, 7 August 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4bwf

Contents

Pex4p-Pex22p disulphide bond mutant

Template:ABSTRACT PUBMED 23896733

Function

[UBCX_YEAST] Catalyzes the covalent attachment of ubiquitin to other proteins. Essential for peroxisome biogenesis. Required for UBC4-independent ubiquitination of PEX5. [PEX22_YEAST] Involved in peroxisome biogenesis (By similarity).

About this Structure

4bwf is a 2 chain structure with sequence from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 2y9o. Full crystallographic information is available from OCA.

Reference

  • Williams C, van den Berg M, Stanley WA, Wilmanns M, Distel B. A disulphide bond in the E2 enzyme Pex4p modulates ubiquitin-conjugating activity. Sci Rep. 2013 Jul 30;3:2212. doi: 10.1038/srep02212. PMID:23896733 doi:10.1038/srep02212

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OCA

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