4doh

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Template:STRUCTURE 4doh

Contents

IL20/IL201/IL20R2 Ternary Complex

Template:ABSTRACT PUBMED 22802649

Function

[IL20_HUMAN] Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

About this Structure

4doh is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Logsdon NJ, Deshpande A, Harris BD, Rajashankar KR, Walter MR. Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12704-9. Epub 2012 Jul 16. PMID:22802649 doi:10.1073/pnas.1117551109

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OCA

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