4axm
From Proteopedia
Contents |
TRIAZINE CATHEPSIN INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 23658062
Function
[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
About this Structure
4axm is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. PMID:23658062 doi:10.1002/cmdc.201300112
