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4axl

From Proteopedia

Revision as of 17:57, 19 June 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4axl

Contents

HUMAN CATHEPSIN L APO FORM WITH ZN

Template:ABSTRACT PUBMED 23658062

Function

[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.

About this Structure

4axl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. PMID:23658062 doi:10.1002/cmdc.201300112

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OCA

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