4aq5

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Template:STRUCTURE 4aq5

Contents 1 Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class) 2 Function 3 About this Structure 4 Reference

Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)

Template:ABSTRACT PUBMED 22841691

Function

[ACHA_TORMA] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

About this Structure

4aq5 is a 5 chain structure with sequence from Torpedo marmorata. Full crystallographic information is available from OCA.

Reference

• Unwin N, Fujiyoshi Y. Gating movement of acetylcholine receptor caught by plunge-freezing. J Mol Biol. 2012 Oct 5;422(5):617-34. Epub 2012 Jul 24. PMID:22841691 doi:10.1016/j.jmb.2012.07.010