3wb8

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Template:STRUCTURE 3wb8

Contents

Crystal Structure of MyoVa-GTD

Template:ABSTRACT PUBMED 23798443

Function

[MYO5A_MOUSE] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.[1]

About this Structure

3wb8 is a 8 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Wei Z, Liu X, Yu C, Zhang M. Structural basis of cargo recognitions for class V myosins. Proc Natl Acad Sci U S A. 2013 Jun 24. PMID:23798443 doi:10.1073/pnas.1306768110
  1. ↑ Chen Y, Wang Y, Zhang J, Deng Y, Jiang L, Song E, Wu XS, Hammer JA, Xu T, Lippincott-Schwartz J. Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol. 2012 Aug 20;198(4):545-60. doi: 10.1083/jcb.201111091. PMID:22908308 doi:10.1083/jcb.201111091

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