4e8b

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Template:STRUCTURE 4e8b

Contents 1 Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli 2 Function 3 About this Structure 4 Reference

Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli

Template:ABSTRACT PUBMED 22925577

Function

[RSME_ECOLI] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.^{[1] [2]}

About this Structure

4e8b is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

• Zhang H, Wan H, Gao ZQ, Wei Y, Wang WJ, Liu GF, Shtykova EV, Xu JH, Dong YH. Insights into the Catalytic Mechanism of 16S rRNA Methyltransferase RsmE (m(3)U1498) from Crystal and Solution Structures. J Mol Biol. 2012 Aug 25. PMID:22925577 doi:10.1016/j.jmb.2012.08.016

1. ↑ Basturea GN, Rudd KE, Deutscher MP. Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family. RNA. 2006 Mar;12(3):426-34. Epub 2006 Jan 23. PMID:16431987 doi:10.1261/rna.2283106
2. ↑ Basturea GN, Deutscher MP. Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA. 2007 Nov;13(11):1969-76. Epub 2007 Sep 13. PMID:17872509 doi:rna.700507