4ebr

From Proteopedia

Revision as of 11:16, 24 July 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4ebr

Contents

Crystal structure of Autophagic E2, Atg10

Template:ABSTRACT PUBMED 22993095

Function

[ATG10_YEAST] E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS). Likely serves as an ATG5-recognition molecule.

About this Structure

4ebr is a 2 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  • Hong SB, Kim BW, Kim JH, Song HK. Structure of the autophagic E2 enzyme Atg10. Acta Crystallogr D Biol Crystallogr. 2012 Oct;68(Pt 10):1409-17. Epub 2012 Sep, 18. PMID:22993095 doi:10.1107/S0907444912034166

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ebr"
Personal tools