4gpo

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Template:STRUCTURE 4gpo

Contents

Oligomeic Turkey Beta1-Adrenergic G Protein-Coupled Receptor

Template:ABSTRACT PUBMED 23435379

Function

[ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.

About this Structure

4gpo is a 2 chain structure with sequence from Meleagris gallopavo. Full crystallographic information is available from OCA.

Reference

  • Huang J, Chen S, Zhang JJ, Huang XY. Crystal structure of oligomeric beta1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat Struct Mol Biol. 2013 Apr;20(4):419-25. doi: 10.1038/nsmb.2504. Epub 2013 Feb, 24. PMID:23435379 doi:10.1038/nsmb.2504

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