4h11

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Template:STRUCTURE 4h11

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy

Template:ABSTRACT PUBMED 23519667

Function

[DLG2_RAT] Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

About this Structure

4h11 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

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