4h4f
From Proteopedia
Contents |
Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis
Template:ABSTRACT PUBMED 23430245
Disease
[CTRC_HUMAN] Hereditary chronic pancreatitis. Note=Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity.
Function
[CTRC_HUMAN] Has chymotrypsin-type protease activity and hypocalcemic activity. [ICIC_HIRME] Inhibits both elastase and cathepsin G.
About this Structure
4h4f is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
