4hu6

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Template:STRUCTURE 4hu6

Contents

Oxime side-chain cross-links in the GCN4-p1 dimeric coiled coil: Cyclic product

Template:ABSTRACT PUBMED 23843311

Function

[GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.

About this Structure

4hu6 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Haney CM, Horne WS. Oxime Side-Chain Cross-Links in an alpha-Helical Coiled-Coil Protein: Structure, Thermodynamics, and Folding-Templated Synthesis of Bicyclic Species. Chemistry. 2013 Aug 19;19(34):11342-51. doi: 10.1002/chem.201300506. Epub 2013, Jul 10. PMID:23843311 doi:10.1002/chem.201300506

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OCA

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