4j5y

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Template:STRUCTURE 4j5y

Contents

Crystal structure of Hfq from Pseudomonas aeruginosa in complex with ATP

Template:ABSTRACT PUBMED 23897473

Function

[HFQ_PSEAE] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).

About this Structure

4j5y is a 6 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Murina V, Lekontseva N, Nikulin A. Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1504-13. doi:, 10.1107/S090744491301010X. Epub 2013 Jul 18. PMID:23897473 doi:10.1107/S090744491301010X

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OCA

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