4kw5

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Template:STRUCTURE 4kw5

M. tuberculosis DprE1 in complex with inhibitor TCA1

Template:ABSTRACT PUBMED 23776209

About this Structure

4kw5 is a 2 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

Reference

  • Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, Mdluli KE, Franzblau S, Chatterjee AK, Johnson K, Mikusova K, Besra GS, Futterer K, Jacobs WR Jr, Schultz PG. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7. doi:, 10.1073/pnas.1309171110. Epub 2013 Jun 17. PMID:23776209 doi:10.1073/pnas.1309171110

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