2mcz

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Template:STRUCTURE 2mcz

Contents

CR1 Sushi domains 1 and 2

Template:ABSTRACT PUBMED 24214979

Function

[CR1_HUMAN] Mediates cellular binding of particles and immune complexes that have activated complement.

About this Structure

2mcz is a 1 chain structure with sequence from Human. Full experimental information is available from OCA.

Reference

  • Park HJ, Guariento M, Maciejewski M, Hauhart R, Tham WH, Cowman AF, Schmidt CQ, Mertens HD, Liszewski MK, Hourcade DE, Barlow PN, Atkinson JP. Using mutagenesis and structural biology to map the binding site for the Plasmodium falciparum merozoite protein PfRh4 on the human immune adherence receptor. J Biol Chem. 2013 Nov 8. PMID:24214979 doi:http://dx.doi.org/10.1074/jbc.M113.520346

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OCA

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