4kwv

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Template:STRUCTURE 4kwv

Contents 1 Crystal Structure of human apo-QPRT 2 Function 3 About this Structure 4 Reference

Crystal Structure of human apo-QPRT

Template:ABSTRACT PUBMED 24038671

Function

[NADC_HUMAN] Involved in the catabolism of quinolinic acid (QA).^[1]

About this Structure

4kwv is a 6 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

• Malik SS, Patterson DN, Ncube Z, Toth EA. The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins. 2013 Aug 28. doi: 10.1002/prot.24406. PMID:24038671 doi:10.1002/prot.24406

1. ↑ Liu H, Woznica K, Catton G, Crawford A, Botting N, Naismith JH. Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. J Mol Biol. 2007 Oct 26;373(3):755-63. Epub 2007 Aug 24. PMID:17868694 doi:10.1016/j.jmb.2007.08.043