3wdg

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Template:STRUCTURE 3wdg

Contents

Staphylococcus aureus UDG / UGI complex

Template:ABSTRACT PUBMED 24150946

Function

[UNG_STAAR] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).

About this Structure

3wdg is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Wang HC, Hsu KC, Yang JM, Wu ML, Ko TP, Lin SR, Wang AH. Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor. Nucleic Acids Res. 2014 Jan 1;42(2):1354-64. doi: 10.1093/nar/gkt964. Epub 2013, Oct 22. PMID:24150946 doi:http://dx.doi.org/10.1093/nar/gkt964

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