4lsh

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Template:STRUCTURE 4lsh

Contents

Ion selectivity of OmpF porin soaked in 0.2M KBr

Template:ABSTRACT PUBMED 24106986

Function

[OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.[1]

About this Structure

4lsh is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

Reference

  • Dhakshnamoorthy B, Ziervogel BK, Blachowicz L, Roux B. A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations. J Am Chem Soc. 2013 Oct 9. PMID:24106986 doi:http://dx.doi.org/10.1021/ja407783a
  1. ↑ Duval V, Nicoloff H, Levy SB. Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. Antimicrob Agents Chemother. 2009 Nov;53(11):4944-8. doi: 10.1128/AAC.00787-09., Epub 2009 Aug 31. PMID:19721064 doi:10.1128/AAC.00787-09

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