2xrf
From Proteopedia
Contents |
Crystal structure of human uridine phosphorylase 2
Function
[UPP2_HUMAN] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
About this Structure
2xrf is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Categories: Human | Uridine phosphorylase | Arrowsmith, C H. | Berg, S Van Der. | Berglund, H. | Bountra, C. | Collins, R. | Edwards, A M. | Flodin, S. | Flores, A. | Graslund, S. | Hammarstrom, M. | Johansson, I. | Karlberg, T. | Kol, S. | Kotenyova, T. | Kouznetsova, E. | Moche, M. | Nordlund, P. | Nyman, T. | Persson, C. | Schuler, H. | Schutz, P. | Siponen, M I. | Thorsell, A G. | Tresaugues, L. | Wahlberg, E. | Weigelt, J. | Welin, M. | Transferase
