2gig

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Template:STRUCTURE 2gig

Contents 1 Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism 2 Function 3 About this Structure 4 See Also 5 Reference

Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism

Template:ABSTRACT PUBMED 16675462

Function

[T2D2_HAEIN] Recognizes the double-stranded sequence GTYRAC and cleaves after Y-3.

About this Structure

2gig is a 4 chain structure with sequence from "bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896. Full crystallographic information is available from OCA.

See Also

• Endonuclease

Reference

• Joshi HK, Etzkorn C, Chatwell L, Bitinaite J, Horton NC. Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism. J Biol Chem. 2006 Aug 18;281(33):23852-69. Epub 2006 May 4. PMID:16675462 doi:M512339200