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4jp8

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Template:STRUCTURE 4jp8

Contents

Crystal structure of Pro-F17H/S324A

Template:ABSTRACT PUBMED 24115021

Function

[TKSU_THEKO] Has a broad substrate specificity with a slight preference to large hydrophobic amino acid residues at the P1 position.

About this Structure

4jp8 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Yuzaki K, Sanda Y, You DJ, Uehara R, Koga Y, Kanaya S. Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain. Protein Sci. 2013 Dec;22(12):1711-21. doi: 10.1002/pro.2371. Epub 2013 Oct 19. PMID:24115021 doi:http://dx.doi.org/10.1002/pro.2371

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OCA

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