Structural highlights
Publication Abstract from PubMed
The IcsA (intracellular spread gene A) autotransporter from Shigella flexneri is a key virulence factor. We identified a stable fragment comprising residues 591 to 758, which corresponds to the autochaperone region of the IcsA passenger domain. We showed that thermal unfolding of the autochaperone region is reversible and determined its crystal structure at 2.0-A resolution.
Crystal Structure of the Autochaperone Region from the Shigella flexneri Autotransporter IcsA.,Kuhnel K, Diezmann D J Bacteriol. 2011 Apr;193(8):2042-5. Epub 2011 Feb 18. PMID:21335457[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Kuhnel K, Diezmann D. Crystal Structure of the Autochaperone Region from the Shigella flexneri Autotransporter IcsA. J Bacteriol. 2011 Apr;193(8):2042-5. Epub 2011 Feb 18. PMID:21335457 doi:10.1128/JB.00790-10