3whd

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Template:STRUCTURE 3whd

Contents

C-type lectin, human MCL

Template:ABSTRACT PUBMED 24101491

Function

[CLC4D_HUMAN] Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.[1]

About this Structure

3whd is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Furukawa A, Kamishikiryo J, Mori D, Toyonaga K, Okabe Y, Toji A, Kanda R, Miyake Y, Ose T, Yamasaki S, Maenaka K. Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL. Proc Natl Acad Sci U S A. 2013 Oct 7. PMID:24101491 doi:http://dx.doi.org/10.1073/pnas.1312649110
  1. ↑ Arce I, Martinez-Munoz L, Roda-Navarro P, Fernandez-Ruiz E. The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur J Immunol. 2004 Jan;34(1):210-20. PMID:14971047 doi:http://dx.doi.org/10.1002/eji.200324230

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