4l16

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 4l16

Contents 1 Crystal structure of FIGL-1 AAA domain in complex with ADP 2 Function 3 About this Structure 4 Reference

Crystal structure of FIGL-1 AAA domain in complex with ADP

Template:ABSTRACT PUBMED 23979136

Function

[FIGL1_CAEEL] Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility.^[1]

About this Structure

4l16 is a 1 chain structure with sequence from Caeel. Full crystallographic information is available from OCA.

Reference

• Peng W, Lin Z, Li W, Lu J, Shen Y, Wang C. Structural insights into unusually strong ATPase activity of the AAA domain of C. elegans fidgetin like-1 protein. J Biol Chem. 2013 Aug 26. PMID:23979136 doi:10.1074/jbc.M113.502559

1. ↑ Luke-Glaser S, Pintard L, Tyers M, Peter M. The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line. J Cell Sci. 2007 Sep 15;120(Pt 18):3179-87. PMID:17878235 doi:10.1242/jcs.015883