3qmc

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Template:STRUCTURE 3qmc

Contents 1 Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1 2 Function 3 About this Structure 4 Reference

Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1

Template:ABSTRACT PUBMED 21407193

Function

[CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.^[1]

About this Structure

3qmc is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237

1. ↑ Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237