3te4

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Template:STRUCTURE 3te4

Contents 1 Crystal structure of dopamine N Acetyltransferase in complex with acetyl-COA from Drosophila Melanogaster 2 Function 3 About this Structure 4 Reference

Crystal structure of dopamine N Acetyltransferase in complex with acetyl-COA from Drosophila Melanogaster

Template:ABSTRACT PUBMED 22716280

Function

[DNAT_DROME] Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.^{[1] [2] [3]}

About this Structure

3te4 is a 1 chain structure with sequence from Drome. Full crystallographic information is available from OCA.

Reference

• Cheng KC, Liao JN, Lyu PC. Crystal Structure of Dopamine N-Acetyltransferase/Acetyl Coenzyme A Complex Provide Insights into the Catalytic Mechanism. Biochem J. 2012 Jun 21. PMID:22716280 doi:10.1042/BJ20120520

1. ↑ Hintermann E, Grieder NC, Amherd R, Brodbeck D, Meyer UA. Cloning of an arylalkylamine N-acetyltransferase (aaNAT1) from Drosophila melanogaster expressed in the nervous system and the gut. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12315-20. PMID:8901578
2. ↑ Brodbeck D, Amherd R, Callaerts P, Hintermann E, Meyer UA, Affolter M. Molecular and biochemical characterization of the aaNAT1 (Dat) locus in Drosophila melanogaster: differential expression of two gene products. DNA Cell Biol. 1998 Jul;17(7):621-33. PMID:9703021
3. ↑ Hintermann E, Jeno P, Meyer UA. Isolation and characterization of an arylalkylamine N-acetyltransferase from Drosophila melanogaster. FEBS Lett. 1995 Nov 13;375(1-2):148-50. PMID:7498465