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4kar
From Proteopedia
Contents |
Crystal structure of FDTS (TM0449) mutant (H53D) with FAD
Template:ABSTRACT PUBMED 24563811
Function
[THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
About this Structure
4kar is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Mathews II. Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef. 2013 Apr 20;Suppl 12:004. PMID:24563811 doi:http://dx.doi.org/10.4172/2157-2526.S12-004
