2zjm

From Proteopedia

Crystal structure of the human BACE1 catalytic domain in complex with N-[1-(5-chloro-2-isopropoxy-3-methoxy-benzyl)-piperidin-4-yl]-2-(4-sulfamoyl-phenoxy)-acetamide

spinqualitylabelsall models 2zjm, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 2zjm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Related: 2zjh, 2zji, 2zjj, 2zjk, 2zjl, 2zjn Gene: BACE1 (Homo sapiens) Activity: Memapsin 2, with EC number 3.4.23.46 Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Beta secretase Contents 1 Structural highlights 2 Evolutionary Conservation 3 See Also

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OCA

Categories: Homo sapiens | Memapsin 2 | Allison, T J. | Munshi, S K. | Pham, P. | Romanowski, M J. | Aspartyl protease | Bace | Fragment-based discovery | Glycoprotein | Hydrolase | Membrane | Protease | Small-molecule inhibitor | Transmembrane | Zymogen