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Publication Abstract from PubMed
The structure of RNA polymerase II in a complex with the inhibitor alpha-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.
Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.,Bushnell DA, Cramer P, Kornberg RD Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1218-22. Epub 2002 Jan 22. PMID:11805306[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Bushnell DA, Cramer P, Kornberg RD. Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1218-22. Epub 2002 Jan 22. PMID:11805306 doi:10.1073/pnas.251664698
