3apz

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Template:STRUCTURE 3apz

Contents

Apo form of Arabidopsis medium/long-chain length prenyl pyrophosphate synthase

Template:ABSTRACT PUBMED 21220764

Function

[SPS3_ARATH] May be involved in the supply of solanesyl diphosphate for ubiquinone-9 biosynthesis in mitochondria. Synthesizes C25 to C45 medium / long-chain products depending on the type of substrate available. Can use geranyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrates, but not dimethylallyl diphosphate.[1] [2] [3] [4]

About this Structure

3apz is a 2 chain structure with sequence from Arath. Full crystallographic information is available from OCA.

Reference

  • Hsieh FL, Chang TH, Ko TP, Wang AH. Structure and mechanism of an Arabidopsis medium/long-chain length prenyl pyrophosphate synthase. Plant Physiol. 2011 Jan 10. PMID:21220764 doi:10.1104/pp.110.168799
  1. ↑ Bouvier F, Suire C, d'Harlingue A, Backhaus RA, Camara B. Molecular cloning of geranyl diphosphate synthase and compartmentation of monoterpene synthesis in plant cells. Plant J. 2000 Oct;24(2):241-52. PMID:11069698
  2. ↑ van Schie CC, Ament K, Schmidt A, Lange T, Haring MA, Schuurink RC. Geranyl diphosphate synthase is required for biosynthesis of gibberellins. Plant J. 2007 Nov;52(4):752-62. Epub 2007 Sep 18. PMID:17877699 doi:http://dx.doi.org/10.1111/j.1365-313X.2007.03273.x
  3. ↑ Ducluzeau AL, Wamboldt Y, Elowsky CG, Mackenzie SA, Schuurink RC, Basset GJ. Gene network reconstruction identifies the authentic trans-prenyl diphosphate synthase that makes the solanesyl moiety of ubiquinone-9 in Arabidopsis. Plant J. 2012 Jan;69(2):366-75. doi: 10.1111/j.1365-313X.2011.04796.x. Epub 2011 , Oct 25. PMID:21950843 doi:http://dx.doi.org/10.1111/j.1365-313X.2011.04796.x
  4. ↑ Hsieh FL, Chang TH, Ko TP, Wang AH. Structure and mechanism of an Arabidopsis medium/long-chain length prenyl pyrophosphate synthase. Plant Physiol. 2011 Jan 10. PMID:21220764 doi:10.1104/pp.110.168799

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