4hi0

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Template:STRUCTURE 4hi0

Contents

Crystal Structure of Helicobacter pylori Urease Accessory Protein UreF/H/G complex

Template:ABSTRACT PUBMED 24115911

Function

[UREF_HELPY] Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity).[HAMAP-Rule:MF_01385] [UREG_HELPY] Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity).[HAMAP-Rule:MF_01389] [UREH_HELPY] Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity).[HAMAP-Rule:MF_01384]

About this Structure

4hi0 is a 6 chain structure with sequence from Campylobacter pylori. Full crystallographic information is available from OCA.

Reference

  • Fong YH, Wong HC, Yuen MH, Lau PH, Chen YW, Wong KB. Structure of UreG/UreF/UreH complex reveals how urease accessory proteins facilitate maturation of Helicobacter pylori urease. PLoS Biol. 2013 Oct;11(10):e1001678. doi: 10.1371/journal.pbio.1001678. Epub 2013, Oct 8. PMID:24115911 doi:http://dx.doi.org/10.1371/journal.pbio.1001678

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