4mxi

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Template:STRUCTURE 4mxi

Contents

ClpP Ser98dhA

Template:ABSTRACT PUBMED 24106749

Function

[CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

About this Structure

4mxi is a 7 chain structure with sequence from Staa8. Full crystallographic information is available from OCA.

Reference

  • Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. J Am Chem Soc. 2013 Oct 9. PMID:24106749 doi:http://dx.doi.org/10.1021/ja4082793

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OCA

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