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4lt7
From Proteopedia
Contents |
Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium
Template:ABSTRACT PUBMED 24302762
Function
[RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
About this Structure
4lt7 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Guillen J, Ferrer-Orta C, Buxaderas M, Perez-Sanchez D, Guerrero-Valero M, Luengo-Gil G, Pous J, Guerra P, Gomez-Fernandez JC, Verdaguer N, Corbalan-Garcia S. Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20503-8. doi:, 10.1073/pnas.1316179110. Epub 2013 Dec 3. PMID:24302762 doi:http://dx.doi.org/10.1073/pnas.1316179110
