4nes

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Template:STRUCTURE 4nes

Contents

Crystal structure of Methanocaldococcus jannaschii UDP-GlcNAc 2-epimerase in complex with UDP-GlcNAc and UDP

Template:ABSTRACT PUBMED 24470206

Function

[WECB_METJA] Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues (By similarity).

About this Structure

4nes is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Chen SC, Huang CH, Shin Yang C, Liu JS, Kuan SM, Chen Y. Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc. Proteins. 2014 Jan 27. doi: 10.1002/prot.24516. PMID:24470206 doi:http://dx.doi.org/10.1002/prot.24516

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