2bnr

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Template:STRUCTURE 2bnr

Contents 1 STRUCTURAL AND KINETIC BASIS FOR HEIGHTENED IMMUNOGENICITY OF T CELL VACCINES 2 Function 3 About this Structure 4 See Also 5 Reference

STRUCTURAL AND KINETIC BASIS FOR HEIGHTENED IMMUNOGENICITY OF T CELL VACCINES

Template:ABSTRACT PUBMED 15837811

Function

[1A02_HUMAN] Involved in the presentation of foreign antigens to the immune system.

About this Structure

2bnr is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta-2 microglobulin
• Major histocompatibility complex
• T-cell receptor

Reference

• Chen JL, Stewart-Jones G, Bossi G, Lissin NM, Wooldridge L, Choi EM, Held G, Dunbar PR, Esnouf RM, Sami M, Boulter JM, Rizkallah P, Renner C, Sewell A, van der Merwe PA, Jakobsen BK, Griffiths G, Jones EY, Cerundolo V. Structural and kinetic basis for heightened immunogenicity of T cell vaccines. J Exp Med. 2005 Apr 18;201(8):1243-55. PMID:15837811 doi:10.1084/jem.20042323
• Chen JL, Dunbar PR, Gileadi U, Jager E, Gnjatic S, Nagata Y, Stockert E, Panicali DL, Chen YT, Knuth A, Old LJ, Cerundolo V. Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL. J Immunol. 2000 Jul 15;165(2):948-55. PMID:10878370