4cd3
From Proteopedia
Contents |
RnNTPDase2 X4 variant in complex with PSB-071
Template:ABSTRACT PUBMED 24462745
Function
[ENTP2_RAT] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
About this Structure
4cd3 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Zebisch M, Baqi Y, Schafer P, Muller CE, Strater N. Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071. J Struct Biol. 2014 Jan 21. pii: S1047-8477(14)00006-9. doi:, 10.1016/j.jsb.2014.01.005. PMID:24462745 doi:http://dx.doi.org/10.1016/j.jsb.2014.01.005
Categories: Schaefer, P. | Straeter, N. | Zebisch, M. | Apyrase | Atpase | Drug design | Hydrolase | Inhibitor | Ntpdase | Purinergic signalling