4cd3

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Template:STRUCTURE 4cd3

Contents

RnNTPDase2 X4 variant in complex with PSB-071

Template:ABSTRACT PUBMED 24462745

Function

[ENTP2_RAT] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.

About this Structure

4cd3 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Zebisch M, Baqi Y, Schafer P, Muller CE, Strater N. Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071. J Struct Biol. 2014 Jan 21. pii: S1047-8477(14)00006-9. doi:, 10.1016/j.jsb.2014.01.005. PMID:24462745 doi:http://dx.doi.org/10.1016/j.jsb.2014.01.005

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