4elx

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Template:STRUCTURE 4elx

Contents 1 Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl 2 Function 3 About this Structure 4 Reference

Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl

Template:ABSTRACT PUBMED 22606952

Function

[MENB_ECOLI] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).^{[1] [2]}

About this Structure

4elx is a 6 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

• Sun Y, Song H, Li J, Jiang M, Li Y, Zhou J, Guo Z. Active Site Binding and Catalytic Role of Bicarbonate in 1,4-Dihydroxy-2-naphthoyl Coenzyme A Synthases from Vitamin K Biosynthetic Pathways. Biochemistry. 2012 May 24. PMID:22606952 doi:10.1021/bi300486j

1. ↑ Young IG. Biosynthesis of bacterial menaquinones. Menaquinone mutants of Escherichia coli. Biochemistry. 1975 Jan 28;14(2):399-406. PMID:1091286
2. ↑ Jiang M, Chen M, Guo ZF, Guo Z. A bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coli. J Biol Chem. 2010 Sep 24;285(39):30159-69. doi: 10.1074/jbc.M110.147702. Epub, 2010 Jul 19. PMID:20643650 doi:10.1074/jbc.M110.147702