4ddl
From Proteopedia
PDE10a Crystal Structure Complexed with Novel Inhibitor
Template:ABSTRACT PUBMED 22365755
About this Structure
4ddl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hu E, Kunz RK, Rumfelt S, Chen N, Burli R, Li C, Andrews KL, Zhang J, Chmait S, Kogan J, Lindstrom M, Hitchcock SA, Treanor J. Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2262-5. Epub 2012 Feb 8. PMID:22365755 doi:10.1016/j.bmcl.2012.01.086
