1oxk is a 12 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
In Saccharomyces cerevisiae, a branched multistep phosphorelay signaling pathway regulates cellular adaptation to hyperosmotic stress. YPD1 functions as a histidine-phosphorylated protein intermediate required for phosphoryl group transfer from a membrane-bound sensor histidine kinase (SLN1) to two distinct response regulator proteins (SSK1 and SKN7). These four proteins are evolutionarily related to the well-characterized "two-component" regulatory proteins from bacteria. Although structural information is available for many two-component signaling proteins, there are very few examples of complexes between interacting phosphorelay partners. Here we report the first crystal structure of a prototypical monomeric histidine-containing phosphotransfer (HPt) protein YPD1 in complex with its upstream phosphodonor, the response regulator domain associated with SLN1.
The yeast YPD1/SLN1 complex: insights into molecular recognition in two-component signaling systems.,Xu Q, Porter SW, West AH Structure. 2003 Dec;11(12):1569-81. PMID:14656441[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
↑ Xu Q, Porter SW, West AH. The yeast YPD1/SLN1 complex: insights into molecular recognition in two-component signaling systems. Structure. 2003 Dec;11(12):1569-81. PMID:14656441
