3ayh

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Template:STRUCTURE 3ayh

Contents 1 Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III 2 Function 3 About this Structure 4 Reference

Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III

Template:ABSTRACT PUBMED 21714024

Function

[RPC9_SCHPO] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.^[1] [RPC8_SCHPO] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA.^{[2] [3]}

About this Structure

3ayh is a 2 chain structure with sequence from Schizosaccharomyces pombe 972h-. Full crystallographic information is available from OCA.

Reference

• Ehara H, Sekine SI, Yokoyama S. Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA Polymerase III. Protein Sci. 2011 Jun 28. doi: 10.1002/pro.682. PMID:21714024 doi:10.1002/pro.682

1. ↑ Proshkina GM, Shematorova EK, Proshkin SA, Zaros C, Thuriaux P, Shpakovski GV. Ancient origin, functional conservation and fast evolution of DNA-dependent RNA polymerase III. Nucleic Acids Res. 2006 Jul 28;34(13):3615-24. Print 2006. PMID:16877568 doi:34/13/3615
2. ↑ Proshkina GM, Shematorova EK, Proshkin SA, Zaros C, Thuriaux P, Shpakovski GV. Ancient origin, functional conservation and fast evolution of DNA-dependent RNA polymerase III. Nucleic Acids Res. 2006 Jul 28;34(13):3615-24. Print 2006. PMID:16877568 doi:34/13/3615
3. ↑ Zaros C, Thuriaux P. Rpc25, a conserved RNA polymerase III subunit, is critical for transcription initiation. Mol Microbiol. 2005 Jan;55(1):104-14. PMID:15612920 doi:10.1111/j.1365-2958.2004.04375.x