4n5d

From Proteopedia

Revision as of 10:23, 18 December 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4n5d

Contents

Tailoring Small Molecules for an Allosteric Site on Procaspase-6: Cpd1

Template:ABSTRACT PUBMED 24259468

Function

[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

About this Structure

4n5d is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Murray J, Giannetti AM, Steffek M, Gibbons P, Hearn BR, Cohen F, Tam C, Pozniak C, Bravo B, Lewcock J, Jaishankar P, Ly CQ, Zhao X, Tang Y, Chugha P, Arkin MR, Flygare J, Renslo AR. Tailoring Small Molecules for an Allosteric Site on Procaspase-6. ChemMedChem. 2013 Nov 20. doi: 10.1002/cmdc.201300424. PMID:24259468 doi:http://dx.doi.org/10.1002/cmdc.201300424

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4n5d"
Personal tools