4mvt
From Proteopedia
Contents |
Crystal structure of SUMO E3 Ligase PIAS3
Function
[PIAS3_HUMAN] Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.[1]
About this Structure
4mvt is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
